Geopolitics and grand strategy are modern concepts of statecraft associated with the rise and decline of Great Powers. This chapter looks at the concept of geopolitics and its significance for grand strategy. It does so by tracing the development of the concepts and showing how the meaning of the concepts evolved in response to changing world historical contexts. It explains why geopolitics and grand strategy are associated with the politics of Great Powers and why these concepts are currently making a comeback. The chapter then goes on to discuss the pitfalls and problems associated with formulating a grand strategy, and why geopolitics is as much about interpretation as it is about objective geographical factors.