The Development of Non-carbohydrate-based Influenza Virus Sialidase Inhibitors

The discovery of drugs is still an unpredictable process. Breakthroughs are often the result of a combination of factors, including serendipity, rational strategies and a few individuals with novel ideas. This monograph series highlights new therapeutic developments which have provided significant steps forward in the fight against disease. Each book deals with an individual drug or drug class which has altered the approach to therapy. Emphasis is placed on the scientific background to the discoveries and the development of the therapy, with an overview of the current state of knowledge of the drugs by experts in the field. The series is aimed at a broad readership, covering biochemistry, pharmacology and clinical aspects, as well as revealing the personal stories behind these milestone developments.