We present recent developments on the syntax of Real, a library for interfacing two Prolog systems to the statistical language R. We focus on the changes in Prolog syntax within SWI-Prolog that accommodate greater syntactic integration, enhanced user experience and improved features for web-services. We recount the full syntax and functionality of Real as well as presenting sister packages which include Prolog code interfacing a number of common and useful tasks that can be delegated to R. We argue that Real is a powerful extension to logic programming, providing access to a popular statistical system that has complementary strengths in areas such as machine learning, statistical inference and visualisation. Furthermore, Real has a central role to play in the uptake of computational biology and bioinformatics as application areas for research in logic programming.