File(s) not publicly available
A convenient approach to (-)-8-epi-swainsonine
journal contributionposted on 2023-06-07, 22:03 authored by Philip J Parsons, Adrian J Murray, Peter Hitchcock
A novel and efficient synthesis of (-)-8-epi-swainsonine 2 is reported. Face selective diol formation from the bicyclic alkene 3 followed by a stereoselective vinylation of the aldehyde and ring closing metathesis gave the indolizidine ring system which was converted into (-)-8-epi-swainsonine
Department affiliated with
- Chemistry Publications
NotesAll synthetic work carried out at Sussex and directed by the principle author PJP, all authors are from Sussex. Describes the total synthesis of the amino sugar epi-swainsonine by the shortest route, invited paper for special issue.
Full text available