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A modified synthesis of 4-chromanones
journal contributionposted on 2023-06-08, 19:32 authored by Brian Cox, Roger D Waigh
Problems in the synthesis of 4-chromanones by condensation of 2-hydroxyacetophenones with formaldehyde can be avoided by the isolation of the Mannich base hydrochlorides and cyclization by titration with potassium hydroxide.
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