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A new route to highly functionalized heterocyclic rings
journal contribution
posted on 2023-06-07, 19:21 authored by Philip J Parsons, Alexander J Waters, Daryl S Walter, Johnathan BoardA novel cascade reaction has been developed for the rapid construction of heterocyclic rings. The cyclization is thermally induced and does not involve the use of metal ions. This highly efficient construction of furans has been developed during studies directed toward the synthesis of the antibiotic lactonamycin.
History
Publication status
- Published
Journal
Journal of Organic ChemistryISSN
0022-3263Publisher URL
External DOI
Issue
4Volume
72Page range
1395-1398Pages
4.0Department affiliated with
- Chemistry Publications
Notes
All the synthetic work was done at Sussex and was directed by PJP who is principle author, one industrial collaborator. A new reaction has been discovered which leads to the formation of complex ring systems.Full text available
- No
Peer reviewed?
- Yes
