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A new route to highly functionalized heterocyclic rings
journal contributionposted on 2023-06-07, 19:21 authored by Philip J Parsons, Alexander J Waters, Daryl S Walter, Johnathan Board
A novel cascade reaction has been developed for the rapid construction of heterocyclic rings. The cyclization is thermally induced and does not involve the use of metal ions. This highly efficient construction of furans has been developed during studies directed toward the synthesis of the antibiotic lactonamycin.
JournalJournal of Organic Chemistry
Department affiliated with
- Chemistry Publications
NotesAll the synthetic work was done at Sussex and was directed by PJP who is principle author, one industrial collaborator. A new reaction has been discovered which leads to the formation of complex ring systems.
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