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A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain

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journal contribution
posted on 2023-06-09, 00:21 authored by Oakley B Cox, Tobias Krojer, Patrick Collins, Octovia Monteiro, Romain Talon, Anthony Bradley, Oleg Fedorov, Jahangir Amin, Brian D Marsden, John SpencerJohn Spencer, Frank von Delft, Paul E Brennan
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Funding

Rescuing Thermally Unstable p53 Mutants with Small Molecules; New Targeted Cancer Therapies.; G1388; ASSOCIATION FOR INTERNATIONAL CANCER RESEARCH; 14-1002

History

Publication status

  • Published

File Version

  • Published version

Journal

Chemical Science

ISSN

2041-6520

Publisher

RSC

External DOI

Issue

3

Volume

7

Page range

2322-2330

Department affiliated with

  • Chemistry Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2016-02-23

First Open Access (FOA) Date

2016-02-23

First Compliant Deposit (FCD) Date

2016-02-23

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    University of Sussex (Publications)

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    Licence

    CC BY 4.0

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