University of Sussex
2024 - Perspective, Comms Biology (LMTK3 nomenclature).pdf (974.48 kB)

A revised nomenclature for the lemur family of protein kinases

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posted on 2024-05-15, 09:39 authored by Gábor M Mórotz, Neil A Bradbury, Oana Caluseriu, Shin-ichi Hisanaga, Christopher C J Miller, Agnieszka Swiatecka-Urban, Heinz-Josef Lenz, Stephen J Moss, Georgios GiamasGeorgios Giamas
The lemur family of protein kinases has gained much interest in recent years as they are involved in a variety of cellular processes including regulation of axonal transport and endosomal trafficking, modulation of synaptic functions, memory and learning, and they are centrally placed in several intracellular signalling pathways. Numerous studies have also implicated role of the lemur kinases in the development and progression of a wide range of cancers, cystic fibrosis, and neurodegenerative diseases. However, parallel discoveries and inaccurate prediction of their kinase activity have resulted in a confusing and misleading nomenclature of these proteins. Herein, a group of international scientists with expertise in lemur family of protein kinases set forth a novel nomenclature to rectify this problem and ultimately help the scientific community by providing consistent information about these molecules.


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Communications Biology




Springer Science and Business Media LLC



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Department affiliated with

  • Biochemistry Publications


University of Sussex

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