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Ageing: repair and transcription keep us from premature ageing
Trichothiodystrophy (TTD) is a complex disorder caused by mutations in the XPD gene which affect both DNA repair and transcription. A mouse with a TTD mutation has now been found to display remarkable signs of premature ageing.
History
Publication status
- Published
Journal
Current BiologyISSN
0960-9822Publisher
ElsevierExternal DOI
Issue
16Volume
12Page range
R550-R551Pages
2.0Department affiliated with
- Sussex Centre for Genome Damage Stability Publications
Full text available
- No
Peer reviewed?
- Yes