Central Nervous System Infection Diagnosis by Next-Generation Sequencing A Glimpse Into the Future.pdf (173.36 kB)
Central nervous system infection diagnosis by next-generation sequencing: a glimpse into the future?
journal contributionposted on 2023-06-10, 02:24 authored by Nguyen T H Mai, Nguyen H Phu, Le Nguyen T Nhu, Nguyen T T Hong, Nguyen H H Hanh, Lam A Nguyet, Tran M Phuong, Angela McBride, Do Quang Ha, Ho D T Nghia, Nguyen V V Chau, Guy Thwaites, Le Van Tan
Japanese encephalitis virus was detected by deep sequencing for the first time in urine of a 16-year-old boy with encephalitis. Seroconversion and polymerase chain reaction analysis confirmed the metagenomics finding. Urine is useful for diagnosis of flaviviral encephalitis, whereas deep sequencing can be a panpathogen assay for the diagnosis of life-threatening infectious diseases.
- Published version
JournalOpen Forum Infectious Diseases
PublisherOxford University Press (OUP)
Page rangeofx046 1-3
Event locationUnited States
Department affiliated with
- Global Health and Infection Publications
Full text available