Central Nervous System Infection Diagnosis by Next-Generation Sequencing A Glimpse Into the Future.pdf (173.36 kB)
Central nervous system infection diagnosis by next-generation sequencing: a glimpse into the future?
journal contribution
posted on 2023-06-10, 02:24 authored by Nguyen T H Mai, Nguyen H Phu, Le Nguyen T Nhu, Nguyen T T Hong, Nguyen H H Hanh, Lam A Nguyet, Tran M Phuong, Angela McBride, Do Quang Ha, Ho D T Nghia, Nguyen V V Chau, Guy Thwaites, Le Van TanJapanese encephalitis virus was detected by deep sequencing for the first time in urine of a 16-year-old boy with encephalitis. Seroconversion and polymerase chain reaction analysis confirmed the metagenomics finding. Urine is useful for diagnosis of flaviviral encephalitis, whereas deep sequencing can be a panpathogen assay for the diagnosis of life-threatening infectious diseases.
History
Publication status
- Published
File Version
- Published version
Journal
Open Forum Infectious DiseasesISSN
2328-8957Publisher
Oxford University Press (OUP)External DOI
Issue
2Volume
4Page range
ofx046 1-3Event location
United StatesDepartment affiliated with
- Global Health and Infection Publications
Full text available
- Yes
Peer reviewed?
- Yes
