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Clubbing together on clamps: The key to translesion synthesis
Translesion synthesis is an important mechanism by which cells replicate past DNA damage. The sliding clamp DNA polymerase processivity factors play a central role in this process. The clamps are dimeric in bacteria and trimeric in eukaryotes and archaea, raising the question of whether more than one polymerase can interact with the clamp simultaneously. Recently published data suggest that this is indeed the case.
History
Publication status
- Published
Journal
DNA RepairISSN
1568-7864Publisher
ElsevierExternal DOI
Issue
3Volume
5Page range
404-407Pages
4.0Department affiliated with
- Sussex Centre for Genome Damage Stability Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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