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Contribution of research networks to a clinical trial of antidepressants in people with dementia
journal contributionposted on 2023-06-08, 14:01 authored by Niall McCrae, Lisa Douglas, Sube Banerjee
BACKGROUND The Mental Health Research Network and Dementia and Neurodegenerative Diseases Research Network were established in the UK to increase research capacity and activity; the former in mental health generally, and the latter specifically in neurodegenerative disorders including dementia. Little evidence exists on the impact of these networks on research in mental health of older people. AIMS To examine research network support to a multi-centre randomised controlled trial of antidepressants in people with depression superimposed on dementia. Method Qualitative questionnaires were completed by principal investigators, trial-funded research workers and clinical study officers (CSOs) of the research networks. RESULTS Research network contribution was much valued by principal investigators and the nine research teams. CSOs boosted the recruitment campaign in a challenging environment and enhanced assessment processes. Some problems with consistency and staff turnover were raised. CONCLUSION Research network input can make an appreciable difference to the process and outcome of a multi-centre clinical trial.
JournalJournal of mental health (Abingdon, England)
Department affiliated with
- Clinical and Experimental Medicine Publications
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