CIRCRES_2016_309982_R1_20161008.pdf (571.33 kB)
Cytomegalovirus as a driver of excess cardiovascular mortality in rheumatoid arthritis: a red herring or a smoking gun?
journal contributionposted on 2023-06-09, 04:47 authored by Alejandra Pera RojasAlejandra Pera Rojas, Iain Broadley, Kevin DaviesKevin Davies, Florian KernFlorian Kern
Rheumatoid arthritis (RA) is the most common inflammatory arthritis worldwide. Apart from its well known manifestations involving the joints (e.g. deformity, swelling, synovial inflammation), there are widespread, extra-articular manifestations that also involve the cardiovascular (CV) system. The consequences of CV involvement are often serious; cerebrovascular disease, ischemic heart disease and CV disease (CVD)-associated death are up to 50% higher in the context of RA leading to a reduction of life-expectancy in these patients of 3-10 years compared with the general population. To date, no satisfactory explanation of this phenomenon has been found, or maybe, it has been overlooked?
- Accepted version
PublisherLippincott, Williams & Wilkins
Department affiliated with
- Clinical and Experimental Medicine Publications
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