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Dialysis and renal transplantation in HIV-infected patients: a European survey

journal contribution
posted on 2023-06-08, 16:43 authored by Joan Carles Trullas, Amanda Mocroft, Federico Cofan, Jérome Tourret, Asunción Moreno, Corinne Isnard Bagnis, Christoph Andreas Fux, Christine Katlama, Peter Reiss, Jens Lundgren, Jose Maria Gatell, Ole Kirk, Jose M Miró, the EuroSIDA Investigators, Martin FIsher
OBJECTIVES To determine prevalence and characteristics of end-stage renal diseases (ESRD) [dialysis and renal transplantation (RT)] among European HIV-infected patients. METHODS Cross-sectional multicenter survey of EuroSIDA clinics during 2008. RESULTS Prevalence of ESRD was 0.5%. Of 122 patients with ESRD 96 were on dialysis and 26 had received a RT. Median age was 47 years, 73% were males and 43% were black. Median duration of HIV infection was 11 years. Thirty-three percent had prior AIDS; 91% were receiving antiretrovirals; and 88% had undetectable viral load. Median CD4(+)T-cell count was 341 cells per cubic millimetre; 20.5% had hepatitis C coinfection. Most frequent causes of ESRD were HIV-associated nephropathy (46%) and other glomerulonephritis (28%). Hemodialysis (93%) was the most common dialysis modality; 34% of patients were on the RT waiting list. A poor HIV control was the reason for exclusion from RT waiting list in 22.4% of cases. All the RT recipients were all alive at the time of the survey. Acute rejection was reported in 8 patients (30%). Functioning graft was present in 21 (80%). CONCLUSIONS This is the first multinational cross-sectional study of ESRD among European HIV population. Low prevalence of ESRD was found. Two-thirds of patients were excluded from RT for non-HIV/AIDS-related pathologies. Most patients had a functioning graft despite a high acute rejection rate.


Publication status

  • Published


JAIDS Journal of Acquired Immune Deficiency Syndromes




Lippincott, Williams & Wilkins





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Department affiliated with

  • BSMS Publications


Martin Fisher is not a lead author but one of the EuroSIDA Investigators

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Peer reviewed?

  • Yes

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