Dimensions of interoception predict premonitory urges and tic severity in Tourette syndrome.pdf (193.38 kB)
Dimensions of interoception predict premonitory urges and tic severity in Tourette syndrome
journal contribution
posted on 2023-06-09, 16:13 authored by Charlotte RaeCharlotte Rae, Dennis Larsson, Sarah Garfinkel, Hugo CritchleyHugo CritchleyInteroceptive processes in Tourette syndrome may foster the premonitory urges that commonly precede tics. Twenty-one adults with TS and 22 controls completed heartbeat tracking and discrimination tasks. Three dimensions of interoception were examined: objective accuracy, metacognitive awareness, and subjective (self-report) sensibility. Trait interoceptive prediction error was calculated as the discrepancy between accuracy and sensibility. Participants with TS had numerically lower interoceptive accuracy on the heartbeat tracking task, and increased self-reported interoceptive sensibility. While these group differences were not significant, the discrepancy between lower interoceptive accuracy and heightened sensibility, i.e. the trait interoceptive prediction error, was significantly greater in TS compared to controls. This suggests a heightened higher-order sensitivity to bodily sensations in TS, relative to a noisier perceptual representation of afferent bodily signals. Moreover, interoceptive sensibility predicted the severity of premonitory sensations and tics. This suggests interventions that work to align dimensions of interoceptive experience in TS hold therapeutic potential.
Funding
Sackler Centre - donation; G1813; SACKLER-DR MORTIMER AND THERESA SACKLER FOUNDATION
History
Publication status
- Published
File Version
- Accepted version
Journal
Psychiatry ResearchISSN
0165-1781Publisher
ElsevierExternal DOI
Volume
271Page range
469-475Department affiliated with
- BSMS Publications
Research groups affiliated with
- Sackler Centre for Consciousness Science Publications
- Sussex Neuroscience Publications
Full text available
- Yes
Peer reviewed?
- Yes