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Enhancing cognition by affecting memory reconsolidation
journal contribution
posted on 2023-06-09, 16:54 authored by Emiliano MerloEmiliano Merlo, Amy L Milton, Barry J EverittFully consolidated associative memories can undergo a retrieval-dependent reconsolidation process, which allows for the updating and strengthening of the original association. Limiting, or so-called boundary, conditions determine whether a particular retrieval event triggers reconsolidation. Manipulating memories at reconsolidation may offer an opportunity to improve cognitive capacities in humans by increasing memory persistence, specificity and accuracy. Also, preventing the reconsolidation of maladaptive memories that characterize some neuropsychiatric disorders, such as post-traumatic stress disorder or drug addiction may offer a novel approach to treatment. Here we review recent advances in understanding and manipulating memory reconsolidation in both animals and humans, and discuss the potential of such interventions in cognitive enhancement.
History
Publication status
- Published
File Version
- Accepted version
Journal
Current Opinion in Behavioral SciencesISSN
2352-1546Publisher
ElsevierExternal DOI
Volume
4Page range
41-47Department affiliated with
- Psychology Publications
Full text available
- Yes
Peer reviewed?
- Yes