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Evidence for causal top-down frontal contributions to predictive processes in speech perception
journal contribution
posted on 2023-06-09, 19:21 authored by Thomas E Cope, Ediz SohogluEdiz Sohoglu, W Sedley, K Patterson, P S Jones, J Wiggins, C Dawson, M Grube, R P Carlyon, T D Griffiths, Matthew H Davis, James B RowePerception relies on the integration of sensory information and prior expectations. Here we show that selective neurodegeneration of human frontal speech regions results in delayed reconciliation of predictions in temporal cortex. These temporal regions were not atrophic, displayed normal evoked magnetic and electrical power, and preserved neural sensitivity to manipulations of sensory detail. Frontal neurodegeneration does not prevent the perceptual effects of contextual information; instead, prior expectations are applied inflexibly. The precision of predictions correlates with beta power, in line with theoretical models of the neural instantiation of predictive coding. Fronto-temporal interactions are enhanced while participants reconcile prior predictions with degraded sensory signals. Excessively precise predictions can explain several challenging phenomena in frontal aphasias, including agrammatism and subjective difficulties with speech perception. This work demonstrates that higher-level frontal mechanisms for cognitive and behavioural flexibility make a causal functional contribution to the hierarchical generative models underlying speech perception.
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- Published
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- Published version
Journal
Nature CommunicationsISSN
2041-1723Publisher
Nature Publishing GroupExternal DOI
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1Volume
8Article number
a2154Department affiliated with
- Psychology Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2019-10-14First Open Access (FOA) Date
2019-10-14First Compliant Deposit (FCD) Date
2019-10-14Usage metrics
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