Fe(III) mediated oxidative radical cyclisation of cyclopropanone acetals
journal contribution
posted on 2023-06-08, 19:31authored byKevin I Booker-Milburn, Andy Barker, Wayne Brailsford, Brian Cox, Tamsin E Mansley
A variety of cyclopropanone acetal derivatives were found to undergo facile Fe(III) mediated oxidative radical cyclisation to the corresponding trisubstituted cyclopentane esters in good yield and with diastereoselectivities as high as 23:1.