Rass_Freedom of Movement.pdf (49.75 kB)
Download fileFreedom of movement
Holliday junction resolvases lock dynamic DNA four-way junctions into specific structural conformations for symmetric DNA cleavage. Single-molecule studies now reveal that resolvases can relax their grip, enabling Holliday junction conformer transitions and branch migration in the enzyme-bound form.
History
Publication status
- Published
File Version
- Accepted version
Journal
Nature Chemical BiologyISSN
1552-4450Publisher
Nature ResearchExternal DOI
Issue
37Volume
15Page range
209-210Department affiliated with
- Sussex Centre for Genome Damage Stability Publications
Research groups affiliated with
- Genome Damage and Stability Centre Publications
Full text available
- Yes
Peer reviewed?
- No