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posted on 2023-06-09, 16:36 authored by Ulrich RassUlrich Rass
Holliday junction resolvases lock dynamic DNA four-way junctions into specific structural conformations for symmetric DNA cleavage. Single-molecule studies now reveal that resolvases can relax their grip, enabling Holliday junction conformer transitions and branch migration in the enzyme-bound form.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Nature Chemical Biology

ISSN

1552-4450

Publisher

Nature Research

External DOI

Issue

37

Volume

15

Page range

209-210

Department affiliated with

  • Sussex Centre for Genome Damage Stability Publications

Research groups affiliated with

  • Genome Damage and Stability Centre Publications

Full text available

  • Yes

Peer reviewed?

  • No

Legacy Posted Date

2019-01-22

First Open Access (FOA) Date

2019-07-21

First Compliant Deposit (FCD) Date

2019-01-22

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    No categories selected

    Keywords

    Holliday junction resovaseshomologous recombination

    Licence

    Copyright not evaluated

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