University of Sussex
Browse

Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023

Download (408.94 kB)
journal contribution
posted on 2025-06-13, 13:12 authored by A Singanayagam, C Moore, S Froude, C Celma, J Stowe, E Hani, KF Ng, P Muir, M Roderick, S Cottrell, DF Bibby, B Vipond, S Gillett, PJ Davis, J Gibb, M Barry, P Harris, F Rowley, J Song, AG Shankar, D McMichael, JM Cohen, A Manian, C Harvey, LS Primrose, S Wilson, DT Bradley, K Paranthaman, S Beard, M Zambon, M Ramsay, V Saliba, S Ladhani, C Williams
Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of enterovirus infection. Between June 2022 and April 2023, twenty cases of severe neonatal enteroviral myocarditis caused by coxsackie B viruses were reported in the United Kingdom. Sixteen required critical care support and two died. Enterovirus PCR on whole blood was the most sensitive diagnostic test. We describe the initial public health investigation into this cluster and aim to raise awareness among paediatricians, laboratories and public health specialists.

History

Publication status

  • Published

File Version

  • Published version

Journal

Eurosurveillance

ISSN

1025-496X

Publisher

European Centre for Disease Control and Prevention (ECDC)

Issue

39

Volume

28

Article number

2300313

Department affiliated with

  • BSMS Publications

Institution

University of Sussex

Full text available

  • Yes

Peer reviewed?

  • Yes