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Long-term follow-up of placental transfusion in full-term infants
journal contributionposted on 2023-06-08, 20:32 authored by Heike RabeHeike Rabe, Judith S Mercer, Deborah A Erickson-Ownes
The effects of redistributing placental blood into healthy full-term newborns at birth by delayed umbilical cord clamping (CC) have been demonstrated in many studies.1 The short-term benefits include higher hemoglobin concentration after birth and increased iron stores until 6 months of age. Early clamping of the cord was introduced in the past to avoid maternal hemorrhage without considering potential neonatal adverse effects. A meta-analysis by McDonald et al1 found no significant differences in postpartum hemorrhage rates when comparing early vs late CC groups in 5 trials that included 2260 women. When that Cochrane review was published, only 1 clinical trial had reported any data on long-term neurodevelopmental outcomes of full-term newborns. Previously, Andersson and colleagues2 reported the outcomes of 4-month-old infants who were randomized to early vs late CC. They did not report any significant difference in scores using the Ages and Stages Questionnaire.
PublisherAmerican Medical Association
Department affiliated with
- Clinical and Experimental Medicine Publications
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