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Memories are made of this: synergy of T cell receptor and cytokine signals in CD4(+) central memory cell survival
journal contributionposted on 2023-06-08, 22:36 authored by Stefano Caserta, Rose Zamoyska
The ability of the immune system to 'remember' a previous encounter with antigen is the hallmark of the adaptive immune response. The signals required for CD4(+) memory T cell survival are not well understood, and a recent paper lends new biochemical insights into how memory T cells might optimally be preserved through the convergence of signals from the engagement of cytokine and antigen-specific T cell receptors.
JournalTrends in Immunology
Department affiliated with
- Clinical and Experimental Medicine Publications
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