Microwave-mediated synthesis of N-methyliminodiacetic acid  (MIDA) boronates

Close, Adam J; Kemmitt, Paul; Emmerson, Matthew K; Spencer, John

final_resubmission_SRO.pdf (687.72 kB)

Microwave-mediated synthesis of N-methyliminodiacetic acid (MIDA) boronates

journal contribution

posted on 2023-06-08, 20:40 authored by Adam J Close, Paul Kemmitt, Matthew K Emmerson, John SpencerJohn Spencer

A library of over 20, mainly aryl or heteroaryl, N-methyliminodiacetic acid (MIDA) boronates have been synthesised. A rapid microwave-mediated (MW) method (5–10 min) has been developed using polyethylene glycol 300 (PEG 300) as solvent. However, acetonitrile (MeCN) and dimethylformamide (DMF) were found to be alternative solvents, the latter especially for 2-substituted aryl boronic acids.

History

Publication status

Published

File Version

Accepted version

Journal

Tetrahedron

ISSN

0040-4020

Publisher

Elsevier

External DOI

https://doi.org/10.1016/j.tet.2014.09.044

Issue

47

Volume

70

Page range

9125-9131

Department affiliated with

Chemistry Publications

Full text available

Yes

Peer reviewed?

Yes

Legacy Posted Date

2015-05-01

First Open Access (FOA) Date

2015-05-01

First Compliant Deposit (FCD) Date

2015-05-01

Microwave-mediated synthesis of N-methyliminodiacetic acid (MIDA) boronates

History

Publication status

File Version

Journal

ISSN

Publisher

External DOI

Issue

Volume

Page range

Department affiliated with

Full text available

Peer reviewed?

Legacy Posted Date

First Open Access (FOA) Date

First Compliant Deposit (FCD) Date

Usage metrics

Categories

Keywords

Licence

Exports