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Monocular Chromatic Contrast Threshold and Achromatic Contrast Sensitivity in Children Born Prematurely

journal contribution
posted on 2023-06-08, 07:42 authored by Timothy L Jackson, Gek L Ong, Morag McIndoe, Lionel G Ripley
Purpose: To study the effect of prematurity on monocular chromatic contrast thresholds (CCT) and achromatic contrast sensitivity (ACS). Design: Case¿control study. Methods: A prospective study of 59 children born at less than 33 weeks¿ gestation was undertaken. Subjects were identified during routine neonatal screening for retinopathy of prematurity and recalled for testing at age 7 to 13 years. Five had stage 1 retinopathy of prematurity, seven had stage 2, and three had stage 3. Sixty-eight full-term children were recruited as controls. Those with major cerebral or eye disease were excluded. The CCT and ACS were measured monocularly in the eye with better visual acuity using static, computer-generated, sinusoidal gratings, displayed on a high-resolution monitor. The CCT and ACS were determined using a randomized double-staircase reversal algorithm. The ACS was measured at five spatial frequencies (0.22, 0.44, 0.88, 1.75, and 3.50 cycles/degree), and the CCT was measured along red¿green and tritan confusion axes. Results: Red¿green (P = .326) and tritan (P = .910) contrast thresholds and ACS (P > .394 for all spatial frequencies) were similar to the control group.


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  • Published


American Journal of Ophthalmology







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  • Engineering and Design Publications


This paper derives from major research activities at the Sussex Eye Hospital (Lead Surgeon Mr AG Casswell), for which I produced the Sussex Gratings Machine. This apparatus has led to various clinical studies which have established that (tritan) colour-vision deficit is a useful measure of the progress of various neurological and ophthalmic conditions. This particular paper refutes work by other authors on the vision of children born prematurely, on the basis that our test results were more reliable, and hence establishes that the SGM is a superior method of colour-vision assessment in the clinical situation.

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