Negative symptoms in first-episode psychosis: clinical correlates and 1-year follow-up outcomes in London Early Intervention Services

Aim Negative symptoms (NS) have been associated with poor outcome and remain difficult to treat in patients with psychosis. This study examined the association of NS with clinical features at first presentation to mental health services for psychosis and with outcomes at 1-year follow-up. Methods Clinical data were utilized from five London Early Intervention Services (EIS) included in the MiData audit database. The sample comprised 484 first-episode psychosis patients with complete Positive and Negative Syndrome Scale data at baseline and 1-year follow-up. Multiple imputation (N?=?50) was conducted to account for missing follow-up data. Results Baseline NS were associated with male gender (B?=?-1.63, P?