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Obtaining snapshots of genetic variation using hemiclonal analysis
journal contribution
posted on 2023-06-08, 12:10 authored by Jessica K Abbott, Ted MorrowHemiclones are naturally occurring or artificially produced individuals that share a single specific genetic haplotype. Natural hemiclones are produced via hybridization between two closely related species, whereas hemiclonal analysis in Drosophila is carried out in the laboratory via crosses with artificially created ‘clone-generator’ females with a specific genetic make-up. Hemiclonal analysis in Drosophila has been applied successfully to date to obtain measures of standing genetic variation for numerous traits. Here, we review the current hemiclonal literature and suggest future directions for hemiclonal research, including its application in molecular and genomic studies, and the adaptation of natural hemiclonal systems to carry out Drosophila-type studies of standing genetic variation.
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Publication status
- Published
Journal
Trends in Ecology & EvolutionISSN
0169-5347Publisher
ElsevierExternal DOI
Issue
7Volume
26Page range
359-368Department affiliated with
- Evolution, Behaviour and Environment Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-08-02Usage metrics
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