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Optical force on diseased blood cells: towards the optical sorting of biological matter

journal contribution
posted on 2023-06-09, 07:33 authored by Juan Sebastian Totero Gongora, Andrea Fratalocchi
By employing a series of massively parallel ab-initio simulations, we study how optical forces act on biological matter subject to morphological disease. As a representative case study, we here consider the case of Plasmodium falciparum on red blood cells (RBC) illuminated by a monochromatic plane wave. Realistic parameters for the geometry and the refractive index are then taken from published experiments. In our theoretical campaign, we study the dependence of the optical force on the disease stage for different incident wavelengths. We show that optical forces change significantly with the disease, with amplitude variation in the hundreds of pN range. Our results open up new avenues for the design of new optical systems for the treatment of human disease.

History

Publication status

  • Published

File Version

  • Published version

Journal

Optics and Lasers in Engineering

ISSN

0143-8166

Publisher

Elsevier

Volume

76

Page range

40-44

Department affiliated with

  • Physics and Astronomy Publications

Research groups affiliated with

  • Atomic, Molecular and Optical Physics Research Group Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2018-07-05

First Compliant Deposit (FCD) Date

2018-07-04

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