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Polar assembly in a designed protein fiber
journal contribution
posted on 2023-06-08, 07:19 authored by Andrew M Smith, Steve F A Acquah, Neil Bone, Harold W Kroto, Maxim G Ryadnov, Marryat S P Stevens, David R M Walton, Derek N WoolfsonBioinspiration: Polar assembly (a feature of many natural protein-based fibrous structures, such as actin, microtubules, intermediate filaments, and collagens) is demonstrated in a straightforward, synthetic, peptide-based fiber system of de novo design (see false-color confocal-microscope image of fibers). This finding opens up possibilities for engineering self-assembling soft materials from the bottom up and with nano-to-microscale precision.
History
Publication status
- Published
Journal
Angewandte Chemie International EditionISSN
1433-7851External DOI
Issue
2Volume
44Page range
325-328Pages
4.0Department affiliated with
- Chemistry Publications
Notes
HK jointly supervised SA with DW and contributed to the experimental design led by and in collaboraton with DW (now at Bristol) and co-authored the paper, all authors are from Sussex. First self asembly of protein fibres based on coiled coli motifsFull text available
- No
Peer reviewed?
- Yes