University of Sussex
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Protocol: Are primary care consultations for insomnia associated with dementia in later life?

journal contribution
posted on 2023-06-09, 07:50 authored by Richard Hoile, Helen Smith, Stephen BremnerStephen Bremner, Jackie Cassell, Philip Rooney, Naji TabetNaji Tabet, Elizabeth FordElizabeth Ford
Insomnia has been defined as a difficulty initiating or maintaining sleep, leading to sleep that is either insufficient or unrefreshing. It is well-established that insomnia is more common in people with dementia, but it is not clear if insomnia predates dementia in these individuals. This latter question is an important one: if it can be shown that people with insomnia are more likely to develop dementia in later life, this may improve our ability to predict an individual’s dementia risk, and possibly to help manage that risk. Several recent studies have found a link between insomnia and later dementia, but typically give little information about the time between the onset of insomnia and the onset of dementia, raising the possibility that the insomnia is an early symptom of dementia, rather than a risk factor or potential cause of the disease. Furthermore, in some studies the link between insomnia and dementia becomes weaker when factors such as depression and sleeping tablet use are taken into account. The proposed study uses primary care records to learn whether people with dementia are more likely to have consulted with their general practitioner (GP) about insomnia 5-10 years earlier, compared to those who do not have dementia.


Astrodem; G1895; Wellcome Trust; 202133/Z/16/Z


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  • Published


None - study protocol to be made open access


Sussex SRO

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  • Division of Medical Education Publications

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  • No

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