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Scientific standards and institutional interests: carcinogenic risk assessment of benoxaprofen in the UK and US
journal contribution
posted on 2023-06-08, 08:12 authored by John AbrahamA systematic methodology for imputing biases in the production and interpretation of scientific knowledge is developed. It is then extensively applied to examine how the interests of industrial and government scientists may have biased the carcinogenic risk assessment of the medical drug `benoxaprofen', in the British and American regulatory contexts. This case study illustrates how commonly agreed technical standards in science can be used to scrutinize the validity of scientific knowledge claims in industry and government, and to identify convergences between patterns of technical inconsistencies and institutional interests in different international contexts. It is argued that the interest-based biases revealed imply deficiencies in regulatory policy. Consequently, a set of political changes are proposed in order to reduce such biases in drug testing and regulation.
History
Publication status
- Published
Journal
Social Studies of ScienceISSN
0306-3127Publisher
SAGE PublicationsExternal DOI
Issue
3Volume
23Page range
387-444Pages
58.0Department affiliated with
- Sociology and Criminology Publications
Full text available
- No
Peer reviewed?
- Yes