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Sickle cell disease: an update
journal contribution
posted on 2023-06-10, 04:01 authored by Emma Conway O'Brien, Sahla Ali, Timothy ChevassutTimothy ChevassutSickle cell disease is a common inherited disorder that is characterised by chronic haemolysis and vaso-occlusive episodes, resulting in severe pain and end-organ damage. The most frequent acute manifestation of sickle cell disease is a painful vaso-occlusive crisis, which can, in some cases, develop into a sickle chest crisis: a life-threatening complication of sickle cell disease that requires early recognition and prompt intervention to prevent progressive respiratory failure. In addition to the acute complications, patients with sickle cell disease are also at risk of a number of chronic complications that require multidisciplinary specialist input.
History
Publication status
- Published
File Version
- Published version
Journal
Clinical Medicine JournalISSN
1470-2118Publisher
Royal College of PhysiciansExternal DOI
Issue
3Volume
22Page range
218-220Event location
EnglandDepartment affiliated with
- Clinical and Experimental Medicine Publications
Full text available
- Yes
Peer reviewed?
- Yes