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The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

journal contribution
posted on 2023-06-07, 13:49 authored by M. O. Leach, K. M. Brindle, J. L. Evelhoch, J. R. Griffiths, M. R. Horsman, A. Jackson, G. C. Jayson, I. R. Judson, M. V. Knopp, R. J. Maxwell, D. McIntyre, A. R. Padhani, P. Price, R. Rathbone, G. J. Rustin, P. S. Tofts, G. M. Tozer, W. Vennart, J. C. Waterton, S. R. Williams, P. Workman
Vascular and angiogenic processes provide an important target for novel cancer therapeutics. Dynamic contrast-enhanced magnetic resonance imaging is being used increasingly to noninvasively monitor the action of these therapeutics in early-stage clinical trials. This publication reports the outcome of a workshop that considered the methodology and design of magnetic resonance studies, recommending how this new tool might best be used.

History

Publication status

  • Published

Journal

British Journal of Cancer

ISSN

0007-0920

Publisher

Nature Publishing Group

Issue

9

Volume

92

Page range

1599-1610

Department affiliated with

  • BSMS Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2007-02-28