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The heart, the brain, and the regulation of emotion
journal contribution
posted on 2023-06-08, 23:44 authored by Sarah Garfinkel, Jessica EcclesJessica Eccles, Hugo CritchleyHugo CritchleyMüller and colleagues1 present a study showing that an electroencephalographic signature of the brain’s representation of internal bodily responses (the amplitude of heartbeat evoked potential) is abnormally attenuated in patients with borderline personality disorder (BPD). This deficit predicts symptoms, including the degree of emotional instability, and correlates with structural differences in the gray matter volume in the insula and the anterior cingulate cortex, brain regions engaged during emotional regulation and implicated in the integrative control of mind and body. Patients with BPD in remission show a more normative heartbeat evoked potential, suggesting that strategies to improve mental and physiological integration may enhance psychotherapeutic interventions for this patient group.
History
Publication status
- Published
Journal
JAMA PsychiatryISSN
2168-622XPublisher
American Medical Association (AMA)External DOI
Issue
11Volume
72Page range
1071-1072Department affiliated with
- BSMS Neuroscience Publications
Full text available
- No
Peer reviewed?
- Yes