posted on 2023-06-08, 12:19authored byMariusz Bobin
Metal-catalysed reactions are highly attractive processes due to their atom economy and open opportunities in the development of new transformations. In the introduction, the theoretical aspects of gold(I) catalysis with examples of gold(I) complexes and their transformations are described with emphasis on enantioselective synthesis. The results and discussion chapter begins with the investigations of a chirally active counterion moiety. The triflic amide moiety was found to be an efficient new counterion and provide opportunity to introduce chiral bidentate ligand on gold(I) complexes. In conclusion, a series of chiral bidentate gold(I) catalysts were synthesised and their catalytic activity demonstrated on model transformations. A number of strategies improve a bidentate ligand for gold(I) catalysts.